Pemetrexed glutamide trimethyl ester; Pemetrexed Impurity D trimethyl ester
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| CAS No. | : 1265908-62-0 |
| Mol F. | : C28H34N6O9 |
| Mol W. | : 598.6 |
| Cat No. | : SA32320 |
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Description
| Product Name | PMT-1 – 1.03 RRT impurity |
| Synonyms | Dimethyl 2-((S)-4-(4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)-5-methoxy-5-oxopentanamido)pentanedioate |
| Related API | Pemetrexed |
| Category | Impurities |
PMT-1 – 1.03 RRT impurity product with CAS: 1265908-62-0 is also known as Dimethyl 2-((S)-4-(4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)-5-methoxy-5-oxopentanamido)pentanedioate. This product can be used as a working standard or secondary reference standard. Additional internal validation as per respective FDA regulations/guidelines may require. It is used in Pemetrexed impurity profiling as per limits and threshold values specified by respective drug legislation, FDA, and pharmacopoeial guidelines. Moreover, Dimethyl 2-((S)-4-(4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)-5-methoxy-5-oxopentanamido)pentanedioate is also used in the process of Abbreviated New Drug Application (ANDA) filing to FDA and toxicity study of respective drug formulation.
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